How It Works

How does OptiHeart® work?

Historic | Ayurvedic

Ceylon cinnamon has historically been associated with heart health in
Sri Lanka and is a common ingredient used in Ayurvedic remedies.

Various studies suggest that ceylon cinnamon, which is rich in proanthocyanidins,
protects against cardiovascular diseases.

The USDA states that a meta-analysis of 14 prospective cohort studies have
suggested that higher dietary intakes of flavonoids such as
Proanthocyanidin were inversely associated with cardiovascular risk.

Why choose OptiHeart®?


1. USDA database for the proanthocyanidin content of selected foods.

2. Salvadó, M., Casanova E., Fernández-Iglesias, A., Arola, L., Bladé, C.   Roles of proanthocyanidin rich extracts in obesity. Food & Function: Royal Society of Chemistry. Spain. 2015.

3. Kimura, H., Ogawa, S., Akihiro, T., Yokota, K. Structural analysis of A-type or B-type highly polymeric proanthocyanidins by thiolytic degradation and the implication in their inhibitory effects on pancreatic lipase. Journal of Chromatography A. Japan. 2011.

4. Cao, A., Wang, J., Gao, H., Zhang, P., Qiu, J. Beneficial clinical effects of grape seed proanthocyanidin extract on the progression of carotid atherosclerotic plaques. Journal of Geriatric Cardiology. China. 2015.

5. Hayward, N., Mcdougall, G., Farag, S., Allwood, J., Austin, C., Campbell, F., Horgan, G., Ranawana, V. Cinnamon shows antidiabetic properties that are species-specific: effects on enzyme activity Inhibition and starch digestion. Plant Foods for Human Nutrition. 2019.

6. Beejmohun, V., Peytavy-Izard, M., Mignon, C., Muscente-Paque, D., Deplanque, X., Ripoll, C., Chapal, N. Acute effect of Ceylon cinnamon extract on postprandial glycemia: Alpha-amylase inhibition, starch tolerance test in rats, and randomized crossover clinical trial in healthy volunteers. BMC Complementary and Alternative Medicine. 2014.

7. Askari, F., Rashidkhani, B., Hekmatdoost, A. Cinnamon may have therapeutic benefits on lipid profile, liver enzymes, insulin resistance, and high-sensitivity C-reactive protein in nonalcoholic fatty liver disease patients. Nutrition Research. New York. 2014.

8. Hlebowicz, J., Darwiche, G., Björgell, O., Almér, L. Effect of cinnamon on postprandial blood glucose, gastric emptying, and satiety in healthy subjects.American Journal of Clinical Nutrition. 2007.

9. Joshi, S., Kuszynski, C., Bagchi, D. The cellular and molecular basis of health benefits of grape seed proanthocyanidin. Current pharmaceutical biotechnology 2. 2001.

10. Chen, C., Yi, L., Jin, X., Zhang, T., Fu, Y., Zhu, J., Mi, M., Zhang, Q., Ling, W., Yu, B. Inhibitory effect of delphinidin on monocyte-endothelial cell adhesion induced by oxidized low-density lipoprotein via ROS/p38MAPK/NF-κB pathway. Cell Biochemistry and Biophysics. 2011.

11. Hong, J., Yang, G., Kim, Y. et al. Anti-inflammatory activity of cinnamon water extract in vivo and in vitro LPS-induced models. BMC Complementary and Alternative Medicine. 2012.

12. Roussel, A., Hininger, I., Benaraba, R., Ziegenfuss, T., Anderson, R. Antioxidant effects of a cinnamon extract in people with impaired fasting glucose that are overweight or obese. Journal of the American College of Nutrition. 2009.

13. Nayak, I., Chinta, R., Jetti, R. Anti-atherosclerotic potential of aqueous extract of Cinnamomum Zeylanicum bark against glucocorticoid induced atherosclerosis in wistar rats. Journal of Clinical and Diagnostic Research. 2017.

13. Nyadjeu, P., Dongmo, A., Nguelefack, T., Kamanyi, A. Antihypertensive and vasorelaxant effects of Cinnamomum Zeylanicum stem bark aqueous extract in rats. Journal of Complementary and Integrative Medicine. 2011.

14. Akilen, R., Pimlott, Z., Tsiami, A., Robinson, N. Effect of short-term administration of cinnamon on blood pressure in patients with prediabetes and type 2 diabetes. Nutrition. 2013.

15. Cassidy, A., Mukamal, K., Liu, L., Franz, M., Eliassen, A., Rimm, E.High anthocyanin intake is associated with a reduced risk of myocardial infarction in young and middle-aged women. Circulation. 2013.

16. Cassidy, A., O’Reilly, E., Kay, C., Sampson, L., Franz, M., Forman, J., Curhan, G., Rimm, E. Habitual intake of flavonoid subclasses and incident hypertension in adults. The American Journal of Clinical Nutrition. 2011.